Endocrinological aspects of the pathophysiology of equine laminitis

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Equine Laminitis: A Revised Pathophysiology

Vasodilation precedes the development of carbohydrate overload laminitis. Circulating laminitis trigger factors activate lamellar enzymes, which lyse the attachments between the distal phalanx and the inner hoof wall. The clinical signs of laminitis occur when the lamellar architecture disintegrates. The amount of pain correlates with the extent of lamellar pathology. A substance produced by St...

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Laminitis and the equine metabolic syndrome.

Although much has been written about laminitis in the context of its association with inflammatory processes, recognition is growing that most cases of laminitis examined by veterinarians in private practice are those associated with pasture grazing, obesity, and insulin resistance (IR). The term 'endocrinopathic laminitis' has been adopted to classify the instances of laminitis in which the or...

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ژورنال

عنوان ژورنال: Equine Veterinary Journal

سال: 2012

ISSN: 0425-1644

DOI: 10.1111/j.2042-3306.2012.00663.x